FGL peptide


CAS No. : 499993-62-3

499993-62-3
Price and Availability of CAS No. : 499993-62-3
Size Price Stock
5mg $105 In-stock
10mg $165 In-stock
25mg $325 In-stock
50mg $520 In-stock
100mg $830 In-stock
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Cat. No. : HY-P3281
M.Wt: 1649.80
Formula: C71H116N20O25
Purity: >98 %
Solubility: H2O : 100 mg/mL
Introduction of 499993-62-3 :

FGL peptide is a fibroblast growth factor receptor (FGFR) modulator and blood-brain barrier-penetrant. FGL peptide activates NCAM-FGFR and FGFR1 signaling pathways. FGL peptide alters expression of apoptosis, signal transduction and metabolism regulator genes in traumatic brain injury contexts. FGL peptide can be used for the research of traumatic brain injury[1][2]. In Vivo:FGL peptide (10 mg/kg; s.c.; every third day) modulates global gene expression in both injured and non-injured adolescent male Wistar rats, with effects supporting neuroprotection, reduced degeneration, and enhanced cellular stability and regenerative processes[1].
FGL peptide (2.6-26.0 µg; i.n.; on PND1, 2, and 3) accelerates maturation of vestibular-dependent sensorimotor coordination skills in newborn Wistar rats, specifically reducing surface righting reflex latency and increasing successful negative geotaxis responses on PND4-6, without affecting general motor activity, muscle strength, or body weight[2].

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