ST 1535
CAS No. : 496955-42-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $40 | In-stock |
| 5mg | $90 | In-stock |
| 10mg | $120 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-105003 |
| M.Wt: | 272.31 |
| Formula: | C12H16N8 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
ST 1535 is a potent and orally active A2A adenosine receptor antagonist. ST 1535 shows antiparkinsonian activity and antitremorigenic effects. ST 1535 has the potential for the research of Parkinson’s disease[1][2].
In Vitro: ST 1535 (0-1000 nM) inhibits forskolin (HY-15371)-induced cAMP formation in CHO cells with IC50s of 510, 353, 950, >1000 nM for hA1, hA2A, hA2B, hA3, respectively[1].
In Vivo: ST 1535 (0, 5, 10 mg/kg; p.o.) antagonizes catalepsy induced by i.c.v. administration with the A2A adenosine agonist CGS 21680 (HY-13201)[1].
ST 1535 (10, 20, 40 mg/kg; i.p.) increases the number of contralateral turns induced by l-DOPA (HY-N0304) in rats[2].
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