Brazilin
CAS No. : 474-07-7
| Size | Price | Stock |
|---|---|---|
| 1mg | $40 | In-stock |
| 5mg | $84 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $196 | In-stock |
| 50mg | $286 | In-stock |
| 100mg | $428 | In-stock |
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| Cat. No. : | HY-N0072 |
| M.Wt: | 286.28 |
| Formula: | C16H14O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 33.33 mg/mL (ultrasonic) |
Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities[1][2][3].
In Vitro:Brazilin (40 µM, 24 h) shows no significant cytotoxic effect on PC12 cells[4].
Brazilin (10 μM, 1 h) reduces H2O2-induced (200 μM, 24 h) cytotoxicity in PC12 Cells[4].
Brazilin (10 μM, 1 h) antagonists H2O2-induced (200 μM, 24 h) cytotoxicity in PC12 Cells[4].
In Vivo:Brazilin (10 mg/kg, i.p, 28 d) alleviates the CMS-induced depressive- and anxiety-like behaviors in adult mice[4].
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