Size | Price | Stock |
---|---|---|
100mg | $66 | In-stock |
500mg | $264 | In-stock |
1 g | Get quote | |
5 g | Get quote | |
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Cat. No. : | HY-13570 |
M.Wt: | 392.46 |
Formula: | C22H29FO5 |
Purity: | >98 % |
Solubility: | DMSO : ≥ 50 mg/mL (127.40 mM) |
Betamethasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities. Betamethasone accelerates fetal lung maturation and induces gene expression and apoptosis[1][2][3][4].
In Vitro: Betamethasone (0.1-1 μM; 12 h) induces gene expression in L929 cells[4].
Betamethasone (0.1-1 μM; 48 h) induces CEM C7 T-cells apoptosis[4].
In Vivo: Betamethasone (0.48 mg; i.v.gtt for 48 h) decreases the hypercapnia-induced increase in CBF due to decreased cerebral vasodilatation[1].
Betamethasone (0.05 ml (1 mg/L); topical injection) ameliorates spinal nerve transection induced mechanical allodynia and thermal hyperalgesia, and reduces the activation of NF-κB and elevation of TNFα and IL-1β, and induces the expression of IL-10 in the rats brain[2].
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