TfR-T12
CAS No. : 344618-30-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $75 | In-stock |
| 5mg | $190 | In-stock |
| 10mg | $320 | In-stock |
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| Cat. No. : | HY-P2297 |
| M.Wt: | 1490.73 |
| Formula: | C71H99N19O15S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range[1][2].
In Vitro: TfR-T12 binds to the TfR and is subsequently internalized into TfR-expressing cells[1].
TfR-T12 is a synthetic peptide obtained by phage display, and is able to bind a different site on TfRs compared with transferrin. TfR-T12 can be chemically conjugated with a pegylated lipid derivative, 3-(N-succinimidyloxyglutaryl)aminopropyl- polyethyleneglycol(2000)- carbamyl distearoyl phosphatidylethanolamine (NHS-PEG2000-DSPE), and used as a functional material to construct the multifunctional lipid vesicles[2].
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