M2I-1


CAS No. : 312271-03-7

312271-03-7
Price and Availability of CAS No. : 312271-03-7
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2mg $80 In-stock
5mg $150 In-stock
10mg $250 In-stock
25mg $550 In-stock
50mg $850 In-stock
100mg $1350 In-stock
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Cat. No. : HY-100341
M.Wt: 404.48
Formula: C19H24N4O4S
Purity: >98 %
Solubility: DMSO : ≥ 32 mg/mL (79.11 mM)
Introduction of 312271-03-7 :

M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC)[1]. IC50 & Target: Mad2[1] In Vitro: M2I-1 may not be sufficiently potent to fully inhibit SAC function in cells[1].
M2I-1 weakens the SAC response, indicating that the compound might be active in cells.[1].

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