TRK-IN-23


CAS No. : 2924344-29-4

2924344-29-4
Price and Availability of CAS No. : 2924344-29-4
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Cat. No. : HY-149965
M.Wt: 364.37
Formula: C20H17FN4O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 2924344-29-4 :

TRK-IN-23 (compound 24b) is a potent and orally active TRK inhibitor with IC50 values of 0.5 nM, 9 nM, 14 nM, 4.4 nM, and 4.8 nM against TRKA, TRKC, TRKAG595R, TRKAF589L, and TRKAG667C, respectively. TRK-IN-23 indues apoptosis of Ba/F3-TRKAG595Rand Ba/F3-TRKAG667C cells[1].

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