Anti-NASH agent 1
CAS No. : 2409685-41-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $355 | In-stock |
| 50mg | $630 | In-stock |
| 100mg | $1010 | In-stock |
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| Cat. No. : | HY-155525 |
| M.Wt: | 423.54 |
| Formula: | C26H33NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Anti-NASH agent 1 (compound 3d)，a derivative of Elafibranor (HY-16737)，is a potent agonist of PPAR-α/δ，targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia，liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect[1]. IC50 & Target:PPAR-α/δ[1]
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