Thalidomide-NH-C5-NH2 (hydrochloride)


CAS No. : 2375194-03-7

2375194-03-7
Price and Availability of CAS No. : 2375194-03-7
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50mg $34 In-stock
100mg $58 In-stock
250mg $133 In-stock
1g $531 In-stock
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Cat. No. : HY-136237
M.Wt: 394.85
Formula: C18H23ClN4O4
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic)
Introduction of 2375194-03-7 :

Thalidomide-NH-C5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

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