PROTAC RIPK degrader-2


CAS No. : 1801547-16-9

1801547-16-9
Price and Availability of CAS No. : 1801547-16-9
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5mg $450 In-stock
10mg $800 In-stock
25mg $1650 In-stock
50mg $2550 In-stock
100mg $3800 In-stock
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Cat. No. : HY-111866
M.Wt: 1060.31
Formula: C52H65N7O11S3
Purity: >98 %
Solubility: DMSO : 150 mg/mL (ultrasonic)
Introduction of 1801547-16-9 :

PROTAC RIPK degraders -2 is a non-peptide PROTAC based on von Hippel-Lindau and targets serine-threonine kinase RIPK2, which is highly selective to the degradation of RIPK2. PROTAC RIPK degrader-2 acts as an activator to increase cell death and activate ion channels in cancer cells. PROTAC RIPK degrader-2 also can inhibit protein interactions, such as receptors and ligands, involved in a variety of diseases, such as cancer and diabetes[1][2]. In Vitro:PROTAC RIPK degrader-2 (0-30 μM, 16 h) dose-dependently downregulates RIPK protein levels in THP-1 cells[1].

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