PKA-IN-1


CAS No. : 179985-52-5

179985-52-5
Price and Availability of CAS No. : 179985-52-5
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50mg $125 In-stock
100mg $190 In-stock
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Cat. No. : HY-115732
M.Wt: 225.25
Formula: C13H11N3O
Purity: >98 %
Solubility: DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 179985-52-5 :

PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM. PKA-IN-1 inhibits cAK in a fashion that is competitive with respect to ATP as substrate[1]. IC50 & Target:IC50: 0.03 μM (cAK)[1] In Vitro:PKA-IN-1 (compounds A1) is ineffective or very poor inhibitors of wheat embryo Ca2+-dependent protein kinase (CDPK) and rat brain Ca2+-dependent protein kinase C (PKC), chicken gizzard myosin light chain kinase (MLCK) and potato tuber cyclic nucleotide-binding phosphatase (Pase).

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