Amino-PEG10-OH
CAS No. : 129449-09-8
| Size | Price | Stock |
|---|---|---|
| 100mg | $37 | In-stock |
| 250mg | $75 | In-stock |
| 1g | $260 | In-stock |
| 5g | $918 | In-stock |
| 10 g | Get quote | |
| 50 g | Get quote | |
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| Cat. No. : | HY-120761 |
| M.Wt: | 457.56 |
| Formula: | C20H43NO10 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG10-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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