Bis-propargyl-PEG8
CAS No. : 1092554-87-4
| Size | Price | Stock |
|---|---|---|
| 100mg | $230 | In-stock |
| 250mg | $280 | In-stock |
| 1g | $570 | In-stock |
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| 10 g | Get quote | |
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| Cat. No. : | HY-115414 |
| M.Wt: | 446.53 |
| Formula: | C22H38O9 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG8 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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