AZA1
CAS No. : 1071098-42-4
(Synonyms: Rac1/Cdc42-IN-1)
| Size | Price | Stock |
|---|---|---|
| 5mg | $247 | In-stock |
| 10mg | $397 | In-stock |
| 25mg | $663 | In-stock |
| 50mg | $945 | In-stock |
| 100mg | $1280 | In-stock |
| 500mg | $2570 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-136383 |
| M.Wt: | 368.43 |
| Formula: | C22H20N6 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);Methanol : 5 mg/mL (ultrasonic;adjust pH to 6 with HCl) |
AZA1 is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induces prostate cancer cells apoptosis and inhibits prostate cancer cells proliferation, migration and invasion[1][2].
In Vitro: AZA1 (Rac1/Cdc42-IN-1) (2-10 μM; 72 hours) blocks the proliferation of human prostate cancer cells 22Rv1 prostate cancer cells[1].
AZA1 (2-10 μM; 24 hours) reduces phosphorylation of PAK1, AKT and BAD in EGF-stimulated 22Rv1 prostate cancer cells[1].
AZA1 (10 μM; 24 hours) blocks Rac1 and Cdc42-dependent cell cycle events in 22Rv1 prostate cancer cells[1].
AZA1 blocks Rac1 and Cdc42-dependent migration of 22Rv1, DU 145 and PC-3 prostate cancer cells[1].
AZA1 affects cell motility and actin rearrangement in prostate cancer cells by suppressing Rac1 and Cdc42 activity via PAK1/2 phosphorylation[1].
In Vivo: AZA1 (Rac1/Cdc42-IN-1) (100 μg; i.p.; daily for 2 weeks) is potent in suppressing human 22Rv1 xenograft growth in mice and improving survival[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- AZA1
- Cat. No.:
- HY-136383
- Quantity:
Your information is safe with us.