IXA6


CAS No. : 1021106-40-0

1021106-40-0
Price and Availability of CAS No. : 1021106-40-0
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1mg $216 In-stock
5mg $540 In-stock
10mg $864 In-stock
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Cat. No. : HY-139212
M.Wt: 441.94
Formula: C22H20ClN3O3S
Purity: >98 %
Solubility: DMSO : 31.25 mg/mL (ultrasonic)
Introduction of 1021106-40-0 :

IXA6 is a novel IRE1/XBP1s activator, and can induce IRE1 RNase activity[1]. In Vitro: IXA6 (10 µM; 4 or 18 h) selectively activates IRE1-XBP1s signaling, and activates the XBP1s transcriptional response[1].
IXA6 (10 µM; 4 h) shows selectivity for IRE1-XBP1s-dependent ER proteostasis remodeling[1].
IXA6 (10 µM; 18 h) reduces secretion of APP through IRE1 activation[1].

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