Tetrabenazine (Racemate)


CAS No. : 718635-93-9

(Synonyms: Ro 1-9569 (Racemate))

718635-93-9
Price and Availability of CAS No. : 718635-93-9
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Cat. No. : HY-B0590A
M.Wt: 317.42
Formula: C19H27NO3
Purity: >98 %
Solubility: DMSO : 50 mg/mL (157.52 mM; Need ultrasonic)
Introduction of 718635-93-9 :

Tetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). (1) The reference for administration is 0.25-0.75 mg/kg IP (2) Injections of tetrabenazine into accumbens core also reduced FR5 lever pressing and increased chow intake. (3) Tetrabenazine (Racemate) reduced extracellular DA and altered DARPP-32 signaling in both substance-P- and enkephalin-containing accumbens neurons. (4) Tetrabenazine (Racemate) inhibits locomotor activity and produces hypothermia upon systemic administration in rats and mice.

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