(1S)-Calcitriol


CAS No. : 61476-45-7

(Synonyms: 1α,25-Dihydroxy-3-epi-vitamin-D3)

61476-45-7
Price and Availability of CAS No. : 61476-45-7
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Cat. No. : HY-10002A
M.Wt: 416.64
Formula: C27H44O3
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 61476-45-7 :

(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1]. In Vitro: 3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1].

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