CAS No. : 578-74-5
(Synonyms: Apigenin-7-O-β-D-glucopyranoside; Cosmosiin; Apigetrin)
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Cat. No. : | HY-N0578 |
M.Wt: | 432.38 |
Formula: | C21H20O10 |
Purity: | >98 % |
Solubility: | DMSO : ≥ 100 mg/mL (231.28 mM) |
Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2].
In Vitro: Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucoside provoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucoside enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells[1].
Apigenin 7-glucoside specifically induces the differentiation of CD34+ cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner[2].
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