Apigenin 7-glucoside

CAS No. : 578-74-5

(Synonyms: Apigenin-7-O-β-D-glucopyranoside; Cosmosiin; Apigetrin)

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Cat. No. : HY-N0578
M.Wt: 432.38
Formula: C21H20O10
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL (231.28 mM)
Introduction of 578-74-5 :

Apigenin-7-glucoside (Apigenin-7-O-β-D-glucopyranoside) exhibits significant anti-proliferative and antioxidant activity and scavenges reactive oxygen species (ROS)[1][2]. In Vitro: Apigenin 7-glucoside exhibits significant anti-proliferative activity against B16F10 melanoma cells after 24 and 48 h of incubation. Apigenin-7-glucoside provoks an increase of subG0/G1, S and G2/M phase cell proportion with a significant decrease of cell proportion in G0/G1 phases. Apigenin-7-glucoside enhances melanogenesis synthesis and tyrosinase activity of B16F10 melanoma cells[1].
Apigenin 7-glucoside specifically induces the differentiation of CD34+ cells towards the erythroid lineage and inhibited the myeloid differentiation. Apigenin 7-glucoside has strong antioxidant activity against reactive oxygen species (ROS) in vitro in a concentration-dependent manner[2].

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