Cyclic somatostatin
CAS No. : 38916-34-6
(Synonyms: SRIF-14; Somatostatin-14)
| Size | Price | Stock |
|---|---|---|
| 1mg | $40 | In-stock |
| 5mg | $72 | In-stock |
| 10mg | $96 | In-stock |
| 25mg | $120 | In-stock |
| 50mg | $180 | In-stock |
| 100mg | $270 | In-stock |
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| Cat. No. : | HY-P0084 |
| M.Wt: | 1637.88 |
| Formula: | C76H104N18O19S2 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (61.05 mM; Need ultrasonic); DMF : 100 mg/mL (61.05 mM; Need ultrasonic) |
Cyclic somatostatin (SRIF-14) is a growth hormone-release inhibiting factor used in the research of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin inhibits the contractile response of isoprenaline with an IC50 value of 13 nM. Cyclic somatostatin can be used for the research of cardiovascular disease[1][2][3]. IC50 & Target:IC50: 13 nM (contractile response of isoprenaline)[1] In Vitro: Cyclic somatostatin (0-10 μM; 15 min) dose-dependently inhibits the contractile response to isoprenaline in rat ventricular cardiomyocytes with an IC50 value of 13 nM[1]. In Vivo: Cyclic somatostatin (5 μg/kg; i.v. per hour once for 18-22 hours) affects visceral metabolism in ruminants[3].
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