EL-102


CAS No. : 1233948-61-2

1233948-61-2
Price and Availability of CAS No. : 1233948-61-2
Size Price Stock
1mg $132 In-stock
5mg $336 In-stock
10mg $540 In-stock
50mg $1140 In-stock
100mg $1800 In-stock
200 mg Get quote
500 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-16187
M.Wt: 384.47
Formula: C19H16N2O3S2
Purity: >98 %
Solubility: DMSO : ≥ 36 mg/mL (93.64 mM)
Introduction of 1233948-61-2 :

EL102 is a inhibitor of HIF1α , Which can inhibit tubulin polymerisation and decreased microtubule stability. target: HIF1α IC 50:20-40 nM.[1] in vitro : EL102 is a cytotoxic agent and also displays cytostatic properties, through flow cytometric analysis of PI-stained cells cultured for 24, 48 and 72 h, following treatment. EL102 induces apoptosis and causes G2/M arrest, preventing the cell from entering into mitosis. In vivo: CWR22 tumours were taken from an in vivo passage, cut into small fragments and transplanted subcutaneously (s.c.) into the flank of 48 nude mice. At day 13, when the tumours were palpable, mice were randomised into 10 groups with 8 mice each and treatment initiated. EL102 12 mg kg 1 via p.o. (0700 hours and 1700 hours daily).[1]

Your information is safe with us.