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Cat.No. Product Name / Activity Added
HY-100001 SKF-96365 (hydrochloride) August 2017
SKF-96365 hydrochloride, an <b>SOCE</b> inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells.
HY-100010 Sulfathiourea August 2017
HY-100011 SR-3029 August 2017
SR 3029 is a potent and highly specific CK1δ/CK1ε inhibitor with the IC50 of 97 nM.
HY-10008 SNS-032 August 2017
SNS-032 is a selective inhibitor of?<b>cyclin-dependent kinase (CDK)</b>, inhibiting <b>CDK2/7/9</b> with?<b>IC<sub>50</sub></b>s?of 48 nM/62 nM/4 nM.
HY-100082 SR 49498 August 2017
HY-10009 Semagacestat August 2017
Semagacestat is a <b>γ-secretase</b> inhibitor, inhibits <b>β-amyloid</b> (<b>Aβ42</b>), <b>Aβ38</b> and <b>Aβ40</b> with <b>IC<sub>50</sub></b> of 10.
HY-10011 SCH 563705 August 2017
SCH 563705 is a potent dual CXCR2(IC50= 1.
HY-100132 Spiro[imidazolidine-4,1'-[1H]indene]-1-acetamide, 3'-fluoro-N-[(4-fluorophenyl)methyl]-2',3'-dihydro-5'-[1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl]-2,5-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]-, (1'S,3'R)- August 2017
HY-10017 SCH 546738 August 2017
SCH 546738 is a novel, potent and non-competitive <b>CXCR3</b> antagonist, the affinity constant (<b>K<sub>i</sub></b>) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.
HY-100184 Sulfur, [4-[[2-(1,1-difluoroethyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-yl]amino]phenyl]pentafluoro-, (OC-6-21)- August 2017
HY-100195 SAR-020106 August 2017
HY-100197 Synaptamide August 2017
Synaptamide is a potent mediator for neurogenic differentiation of NSCs acting through PKA/CREB activation.
HY-100200 SMER28 August 2017
SMER28 is an <b>autophagy</b> activator acting via an mTOR-independent mechanism.
HY-100209 Sufugolix August 2017
Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone (<b>LHRH</b>) receptor antagonist with an <b>IC<sub>50</sub></b> of 0.
HY-100216 SPDP August 2017
SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.
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