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Featured Products
HY-10005  |  Flavopiridol
HY-10008  |  SNS-032
HY-10012  |  AZD-5438
HY-10014  |  R547
HY-10032  |  PF 477736
HY-10087  |  Navitoclax
HY-10128  |  ZM-447439
HY-10161  |  Tozasertib
HY-10180  |  MLN8054
HY-10192  |  NVP-TAE 684
HY-10228  |  Motesanib
HY-10249  |  GSK-690693
HY-10355  |  AKT inhibitor VIII
HY-10358  |  MK 2206 (dihydrochloride)
HY-10992  |  AZD-7762
HY-10997  |  PCI-32765
HY-11001  |  PHA-793887
HY-11002  |  CP-466722
HY-11007  |  GNF-2
HY-11009  |  CGP60474
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Products |  Featured Products
Cat.No. Product Name / Activity Added
HY-10997 PCI-32765 October 2017
PCI-32765 is a selective, irreversible <b>Btk</b> inhibitor with <b>IC<sub>50</sub></b> value of 0.
 
HY-11001 PHA-793887 October 2017
PHA-793887 is a novel pan-cdk inhibitor, including cdk1, cdk2, cdk4, cdk5, cdk7, and cdk9 with IC50 in the 5 to 140 nM range.
 
HY-11002 CP-466722 October 2017
CP-466722 is rapidly reversible potential ATM kinase inhibitor.
 
HY-11007 GNF-2 October 2017
GNF-2 is a highly selective non-ATP competitive inhibitor of oncogenic Bcr-Abl activity (IC50 = 0.
 
HY-11009 CGP60474 October 2017
CGP60474 is a promising inhibitor of PKC with a high degree of selectivity versus other serine/threonine and tyrosine kinases and show competitive kinetics relative to ATP.
 
HY-30237 Roscovitine October 2017
Roscovitine is a potent and selective <b>CDK</b> inhibitor with <b>IC<sub>50</sub></b> of 0.
 
HY-50662 A-769662 October 2017
A-769662 is a potent, reversible <b>AMPK</b> activator with EC<sub>50</sub> of 0.
 
HY-50686 Tivantinib October 2017
Tivantinib is a novel and highly selective <b>c-Met</b> tyrosine kinase inhibitor with <b>K<sub>i</sub></b> of 355 nM.
 
HY-50767 Palbociclib October 2017
Palbociclib is a highly specific inhibitor of <b>Cdk4</b> (<b>IC<sub>50</sub></b>=11 nM) and <b>Cdk6</b> (<b>IC<sub>50</sub></b>=16 nM), having no activity against a panel of 36 additional protein kinases.
 
HY-50878 Crizotinib October 2017
Crizotinib is a potent inhibitor of <b>c-Met</b> and <b>ALK</b> with <b>IC<sub>50</sub></b> of 11 nM and 24 nM in cell-based assays, respectively.
 
HY-50907 ABT-737 October 2017
ABT-737 is a BH3 mimetic inhibitor of?<b>Bcl-xL</b>,?<b>Bcl-2</b>?and?<b>Bcl-w</b>?with?<b>EC<sub>50</sub></b>?of 78.
 
HY-50940 AT7519 October 2017
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM; less potent to CDK3 and little active to CDK7.
 
HY-50946 Imatinib (Mesylate) October 2017
Imatinib Mesylate is a known inhibitor of the <b>c-Kit</b>, <b>Bcr-Abl</b>, and <b>PDGFR</b> tyrosine kinases, inhibits the SLF-dependent activation of c-Kit<sup>wt</sup> kinase with <b>IC<sub>50</sub></b> of ~100 nM, which is similar to the concentration requires for inhibition of Bcr-Abl and PDGFR.
 
HY-70044 GSK-1070916 October 2017
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.
 
HY-70061 Aurora A inhibitor I October 2017
Aurora A inhibitor I is a selective Aurora A inhibitor (Aurora A: IC50=0.
 
 
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