Size | Price | Stock |
---|---|---|
5mg | $60 | In-stock |
10mg | $100 | In-stock |
25mg | $180 | In-stock |
50mg | $330 | In-stock |
100mg | $490 | In-stock |
200 mg | Get quote | |
500 mg | Get quote | |
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Cat. No. : | HY-100032 |
M.Wt: | 383.40 |
Formula: | C19H21N5O4 |
Purity: | >98 % |
Solubility: | DMSO : ≥ 100 mg/mL (260.82 mM) |
PD 117519 (CI947) is an A2A adenosine agonist which has shown oral antihypertensive activity in pharmacological animal models[1][2]. IC50 & Target:A2A adenosine[1] In Vivo: PD 117519 (2-10 mg/kg; oral administration; 16-24 hours; male beagle dogs) treatment produces significant hemodynamic changes at Tmax (4 hours) follows by acute coronary vascular injury that is evident at 16 hours postdosing.Treatment with 2 or 10 mg/kg of PD 117519 produces significant increases in mean heart rate and decreases in mean indirectsystolic blood pressure at time of highest drug exposure, 4 hours postdosing[3].
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