Quinagolide (hydrochloride)
CAS No. : 94424-50-7
(Synonyms: CV205-502 hydrochloride)
| Size | Price | Stock |
|---|---|---|
| 5mg | $320 | In-stock |
| 10mg | $510 | In-stock |
| 50mg | $1400 | In-stock |
| 100mg | $1900 | In-stock |
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| Cat. No. : | HY-13736A |
| M.Wt: | 432.02 |
| Formula: | C20H34ClN3O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 3.85 mg/mL (8.91 mM; Need ultrasonic) |
Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer[1][2]. In Vitro:Quinagolide hydrochloride (100 nM; 48 h) reduces non-ergot dopamine receptor 2 (DRD2) mRNA expression in ectopic lines[2]. Quinagolide hydrochloride (100 nM; 48 h) inhibits the invasive properties of endometrial mesenchymal stromal cells (E-MSCs)[2]. Quinagolide hydrochloride (100 nM; 24 h) significantly reduces the endothelial differentiation of E-MSCs[2]. In Vivo:Quinagolide hydrochloride (0.03-0.6 mg/kg; s.c. once daily for 2 month) effectively inhibits tumor growth in vivo[1].
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