Vonoprazan (Standard)
CAS No. : 881681-00-1
(Synonyms: TAK-438 (Standard))
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| Cat. No. : | HY-100007R |
| M.Wt: | 345.39 |
| Formula: | C17H16FN3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (289.53 mM; Need ultrasonic) |
Vonoprazan (Standard) is the analytical standard of Vonoprazan. This product is intended for research and analytical applications. Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori[1][2][3]. IC50 & Target:IC50: 19 nM (porcine gastric H+,K+-ATPase, at pH 6.5)[2]
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