BAPTA
CAS No. : 85233-19-8
| Size | Price | Stock |
|---|---|---|
| 100mg | $60 | In-stock |
| 200mg | $72 | In-stock |
| 500mg | $108 | In-stock |
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| 5 g | Get quote | |
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| Cat. No. : | HY-100168 |
| M.Wt: | 476.43 |
| Formula: | C22H24N2O10 |
| Purity: | >98 % |
| Solubility: | DMSO : 15.62 mg/mL (32.79 mM; ultrasonic and warming and heat to 60°C); 1M NaOH : 33.33 mg/mL (69.96 mM; ultrasonic and adjust pH to 11 with NaOH) |
BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2].
IC50 & Target: Calcium[1]
In Vitro: BAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca2+]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells[3].
BAPTA (0-10 mM) inhibits phospholipase C (PLC) activity in a dose-dependent manner, and is unrelated to Ca2+[2].
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