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HY-100008

CAS:81485-25-8

 (Synonyms  NIK333)
81485-25-8  Technical Data: Price and Availability of  Cas No:81485-25-8

Cas : 81485-25-8 M.Wt: 302.451
Cas : 81485-25-8 Formula: C20H30O2
Cas : 81485-25-8 Purity: >98 %
Cas : 81485-25-8 Storage: at 20℃ 2 years
Cas : 81485-25-8 Solubility: DMSO: ≥ 100 mg/mL;<br/>In vivo: Peretinoin is dissolved in DMSO (3 mg/mL) and then diluted with water (DMSO: water=1:1).
Cas : 81485-25-8 Name: Peretinoin
USD
5mg/$210 In-stock
10mg/$350 In-stock
50mg/$850 In-stock
100mg/$1300 In-stock
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5g Get quote
>10g Get quote
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81485-25-8  Data Sheet:
 
Introduction of 81485-25-8 :
Peretinoin is an oral acyclic retinoid, inhibits HCV RNA amplification and virus release by altering lipid metabolism. Target: HCV in vitro: Peretinoin is an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma. Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors, such as retinoid X receptor and retinoic acid receptor. Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism. Peretinoin suppresses the RNA replication of H77S.3/GLuc2A most efficiently and its EC50 was 9 μM. Peretinoin may reduce the recurrence of hepatocellular carcinoma (HCC) following surgical ablation of primary tumours. Peretinoin inhibits RNA replication for all genotypes and showed the strongest antiviral effect among the retinoids tested. in vivo: In addition, Peretinoin prevents the development of hepatoma in several different hepatoma models.
 
References on 81485-25-8 :
 

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