Size | Price | Stock |
---|---|---|
100mg | $7 | In-stock |
250mg | $11 | In-stock |
1g | $38 | In-stock |
5g | $104 | In-stock |
10g | $190 | In-stock |
25g | $469 | In-stock |
50 g | Get quote | |
100 g | Get quote | |
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Cat. No. : | HY-100216 |
M.Wt: | 312.36 |
Formula: | C12H12N2O4S2 |
Purity: | >98 % |
Solubility: | DMSO : 155 mg/mL (496.22 mM; Need ultrasonic) |
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1][2]. In Vitro: Equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5) are activated using SPDP.
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