CBR-5884


CAS No. : 681159-27-3

681159-27-3
Price and Availability of CAS No. : 681159-27-3
Size Price Stock
5 mg Get quote
10 mg Get quote
20 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-100012
M.Wt: 336.39
Formula: C14H12N2O4S2
Purity: >98 %
Storage: at 20℃ 2 years
Solubility: H2O : < 0.1 mg/mL (insoluble); DMSO : 50 mg/mL (148.64 mM; Need ultrasonic)
Introduction of 681159-27-3 :

CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis[1]. IC50 & Target: PHGDH, serine synthesis[1] In Vitro: CBR-5884 (15 or 30 μM; 3-5 days) selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis.

Your information is safe with us.