Size | Price | Stock |
---|---|---|
5mg | $50 | In-stock |
10mg | $85 | In-stock |
25mg | $175 | In-stock |
50mg | $280 | In-stock |
100mg | $450 | In-stock |
200 mg | Get quote | |
500 mg | Get quote | |
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Cat. No. : | HY-N7062 |
M.Wt: | 365.45 |
Formula: | C19H19N5OS |
Purity: | >98 % |
Solubility: | DMSO : 100 mg/mL (273.64 mM; Need ultrasonic) |
JNJ-1661010 (Takeda-25) a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with IC50s of 34 and 33 nM for rat FAAH and human FAAH, respectively. JNJ-1661010 can cross the blood-brain barrier and used as broad-spectrum analgesics[1][2].
IC50 & Target: IC50: 34 nM (rat FAAH) and 33 nM (human FAAH)[1]
In Vivo: JNJ-1661010 (Takeda-25; i.p.; 50 mg/kg) diminishes thermal hyperalgesia in the inflammatory rat carrageenan paw model[2].
JNJ-1661010 (i.p.; 10 mg/kg) has a T1/2 of 35 mins, a CL of 0.032 mL/min/kg, and a Cmax of 1.58 μM for rats[1].
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