Quisqualic acid
CAS No. : 52809-07-1
(Synonyms: L-Quisqualic acid)
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| Cat. No. : | HY-12597 |
| M.Wt: | 189.13 |
| Formula: | C5H7N3O5 |
| Purity: | >98 % |
| Solubility: | H2O : 2 mg/mL (10.57 mM; ultrasonic and warming and heat to 60°C); DMSO : 12.5 mg/mL (66.09 mM; ultrasonic and warming and heat to 60°C) |
Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC50 of 45 nM and a Ki of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica[1][2]. In Vitro: Quisqualic acid is an agonist of AMPA and metabotropic glutamate receptors. Quisqualic acid activates mGluR2R (EC50=108 μM; Ki=113 μM) and mGluR4R (EC50=593 μM; Ki=112 μM)[1].
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