Elastatinal
CAS No. : 51798-45-9
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| Cat. No. : | HY-100397 |
| M.Wt: | 512.56 |
| Formula: | C21H36N8O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Elastatinal is a potent and competitive inhibitor of elastase, with a Ki of 0.21 μM. Elastatinal more potently inhibits pancreatic elastase versus leucocyte elastase. Elastatinal shows no activity on human leucocyte chymotrypsin-like protease[1][2][3][4].
In Vitro: Elastatinal inhibits the binding of acetyl-alanyl-alanyl-alanine pnitroanilide and acetyl-alanyl-alanyl-alanine methyl ester to elastase, with Kis of 0.24 μM and 0.21 μM, respectively[1].
Elastatinal (5-20 μM) suppresses the enhanced osteoclast differentiation by neutrophils[3].
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