Y-33075 (hydrochloride)


CAS No. : 471843-75-1

(Synonyms: Y-39983)

471843-75-1
Price and Availability of CAS No. : 471843-75-1
Size Price Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-10068
M.Wt: 316.79
Formula: C16H17ClN4O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 471843-75-1 :

Y-33075 hydrochloride (Y-39983) is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM. In Vitro:Y-33075 hydrochloride (Y-39983) (10 μM) extends neurites in the retinal ganglion cells (RGCs) compared with those in RGCs treated without Y-39983[2].
Y-33075 hydrochloride (Y-39983, 1 μM) inhibits the contraction of rabbit ciliary artery segments evoked by histamine in Ca2+-free solutions. Y-33075 hydrochloride (10 μM) shows no effect on the [Ca2+]i increase with the high-potassium (high-K) solution[3].

Your information is safe with us.