Alfacalcidol
CAS No. : 41294-56-8
(Synonyms: 1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3)
| Size | Price | Stock |
|---|---|---|
| 5mg | $88 | In-stock |
| 10mg | $132 | In-stock |
| 25mg | $264 | In-stock |
| 50mg | $418 | In-stock |
| 100mg | $660 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-10003 |
| M.Wt: | 400.64 |
| Formula: | C27H44O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL (124.80 mM) |
Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis[1][2][3][4].
IC50 & Target: VDR[2]
In Vivo: Alfacalcidol (0.025-0.1 mg/kg; p.o.; five times a week; for 3 months) exerts bone-protective effects independently of its Ca-related effects, and is in this respect superior to vitamin D(3), and that the skeletal actions of alfacalcidol take place, at least in part, independently of suppression of PTH[3].
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