TACA
CAS No. : 38090-53-8
(Synonyms: trans-4-Aminocrotonic acid)
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $120 | In-stock |
| 50mg | $420 | In-stock |
| 100mg | $670 | In-stock |
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| Cat. No. : | HY-100800 |
| M.Wt: | 101.10 |
| Formula: | C4H7NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble); H2O : 20 mg/mL (197.82 mM; ultrasonic and warming and heat to 60°C) |
TACA (trans-4-Aminocrotonic acid) is a potent agonist of GABAA and GABAC receptors (KD= 0.6 μM). TACA also is GABA uptake inhibitor and substrate for GABA-T. TACA produces late biphasic responses in the MPG neurons[1][2][3]. IC50 & Target: KD: 0.6 μM (GABAC)[1]. In Vivo: TACA is a potent competitive inhibitor of GABA uptake in rat brain slices and thus is possibly a substrate for the GABA uptake system[3].
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