SMER28
CAS No. : 307538-42-7
| Size | Price | Stock |
|---|---|---|
| 5mg | $66 | In-stock |
| 10mg | $92 | In-stock |
| 25mg | $185 | In-stock |
| 50mg | $356 | In-stock |
| 100mg | $686 | In-stock |
| 200mg | $1122 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-100200 |
| M.Wt: | 264.12 |
| Formula: | C11H10BrN3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 32 mg/mL (121.16 mM) |
SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide. In Vitro: SMER28 (5-200 μM; 24 hours) shows a dose dependent decline of cell viability[4]. In Vivo: SMER28 (15-65 mg/kg; i.h.; daily, two days before irradiation and during the three days of irradiation) significantly protects against post-irradiation weight loss and enhances survival of mice at 65 mg/kg[5].
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