TMI-1


CAS No. : 287403-39-8

(Synonyms: WAY-171318)

287403-39-8
Price and Availability of CAS No. : 287403-39-8
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10mg $175 In-stock
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Cat. No. : HY-101448
M.Wt: 398.50
Formula: C17H22N2O5S2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 287403-39-8 :

TMI-1 is a potent inhibitor of disintegrin metalloenzyme 17 (ADAM17) and other MMPs. TMI-1 inhibits LPS-induced TNF-α secretion in human primary monocytes, and human whole blood[1]. TMI-1 selectively induces caspase-dependent apoptosis in triple negative (TN) and ERBB2-overexpressing breast tumor cell lines[2].

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