Size | Price | Stock |
---|---|---|
1mg | $130 | Get quote |
5mg | $390 | Get quote |
10mg | $620 | Get quote |
50 mg | Get quote | |
100 mg | Get quote | |
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Cat. No. : | HY-100645 |
M.Wt: | 306.32 |
Formula: | C14H18N4O4 |
Purity: | >98 % |
Solubility: | 10 mM in DMSO |
Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim[1].
In Vitro: Trimethoprim 3-oxide is the primary metabolite of trimethoprim[1].
Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates in human liver microsomes (HLMs). The CYP1A inhibitor α-Naphthoflavone inhibits Trimethoprim 3-oxide formation, however, other competitive P450 inhibitors has no obvious inhibition on the formation[1].
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