MrgprX2 antagonist-3


CAS No. : 2642174-19-2

2642174-19-2
Price and Availability of CAS No. : 2642174-19-2
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5mg $140 In-stock
10mg $225 In-stock
25mg $450 In-stock
50mg $720 In-stock
100mg $1150 In-stock
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Cat. No. : HY-145193
M.Wt: 337.41
Formula: C16H20FN3O2S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 2642174-19-2 :

MrgprX2 antagonist-3 is an MrgprX2 antagonist extracted from patent WO2021092240A1, example E117. MrgprX2 antagonist-3 can be used for the research of inflammatory disorders of the skin[1]. IC50 & Target: MrgprX2[1] In Vitro: MRGPRX2, a member of the Mas-related gene family, was found to be expressed in sensory neurons, mast cells and, most recently, in keratinocytes. MRGPRX2 mRNA is present in adipose tissue, esophagus, urinary bladder, lungs with the highest levels found in skin. Activation of MRGPRX2 leads to mast cell degranulation with subsequent pseudo-allergic reactions[2].

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