Tz-Thalidomide


CAS No. : 2087490-42-2

2087490-42-2
Price and Availability of CAS No. : 2087490-42-2
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5mg $160 In-stock
10mg $260 In-stock
25mg $520 In-stock
50mg $830 In-stock
100mg $1330 In-stock
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Cat. No. : HY-101460
M.Wt: 571.58
Formula: C29H29N7O6
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 2087490-42-2 :

Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 μM (BRD4-1) and 62.55 μM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, itcontains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups[1]. IC50 & Target:46.25 μM (BRD4-1), 62.55 μM (BRD4-2)[1]

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