CAS No. : 1913252-04-6

Price and Availability of CAS No. : 1913252-04-6
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Cat. No. : HY-100846
M.Wt: 542.68
Formula: C30H38N8O2
Purity: >98 %
Storage: at 20℃ 2 years
Solubility: 10 mM in DMSO
Introduction of 1913252-04-6 :

JQEZ5 is a novel and potent EZH2 inhibitor. IC50 & Target: EZH2[1] In Vivo: Animals treated with JQEZ5 exhibit rapid and pronounced tumor regression over the three week treatment course. H3K27me3 levels are largely reduced with treatment further confirming the on-target effect of JQEZ5 in mice. The level of H3K27me3 is largely reduced with the treatment without effect on EZH2 levels in both the tumor and in the lung tissue of JQEZ5 treated animals[1].

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