UK-240455
CAS No. : 178908-09-3
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|---|---|---|
| 1mg | $571 | Get quote |
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| 10 mg | Get quote | |
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| Cat. No. : | HY-19391 |
| M.Wt: | 368.19 |
| Formula: | C11H11Cl2N3O5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist. IC50 & Target: NMDA[1] In Vivo: UK-240455 is a potent and selective N-methyl D-aspartate (NMDA) glycine site antagonist. Following i.v. administration of UK-240455 to male rats, UK-240455 has a clearance of 12 mL/min/kg and a volume of distribution of 0.4 L/kg. The plasma concentration of UK-240455 decreases with an apparent half-life of 0.4 h. Analysis of urine (0 to 24 h) for unchanged UK-240455 indicates that 57% of the dose administered is excreted unchanged in the urine. The urinary clearance of UK-240455 in the rat is therefore 7 mL/min/kg. Following oral administration of UK-240455 to male rats, the apparent elimination half-life of UK-240455 from plasma following oral administration is 1.6 h[1].
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Inquiry Information- Product Name:
- UK-240455
- Cat. No.:
- HY-19391
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