CAS No. : 1784751-18-3

Price and Availability of CAS No. : 1784751-18-3
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5mg $120 In-stock
10mg $180 In-stock
50mg $720 In-stock
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Cat. No. : HY-100114
M.Wt: 351.32
Formula: C20H12F3N3
Purity: >98 %
Storage: at -20℃ 3 years
Solubility: 10 mM in DMSO
Introduction of 1784751-18-3 :

TA-01 potently inhibits CK1ε, CK1δ,and p38α (IC50values are 6.4, 6.8, and 6.7 nM respectively). IC50 value: 6.4/6.8/6.7 nM Target: CK1ε/ CK1δ/p38α MAPK in vitro: TA-01 inhibitors inhibit cardiac development when applied at 5 μM. TA-01 shows an almost complete inhibition of cardiogenesis when applied at 5 μM. TA-01 shows reduced expression of all tested mesoderm markers and the pre-cardiac marker Isl-1.

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