Size | Price | Stock |
---|---|---|
5mg | $132 | In-stock |
10mg | $220 | In-stock |
50mg | $660 | In-stock |
100mg | $880 | In-stock |
200 mg | Get quote | |
500 mg | Get quote | |
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Cat. No. : | HY-100114 |
M.Wt: | 351.32 |
Formula: | C20H12F3N3 |
Purity: | >98 % |
Solubility: | DMSO : 50 mg/mL (142.32 mM; Need ultrasonic) |
TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 acts as a cardiogenic inhibitor. IC50 & Target: IC50: 6.4 nM (CK1ε), 6.8 nM (CK1δ), 6.7 nM (p38 MAPK)[1] In Vitro: TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively. TA-01 (5 μM) is not cytotoxic, completely inhibits cardiogenesis, but induces cardiogenesis at lower concentration[1].
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