Fluazinam impurity 1


CAS No. : 169327-87-1

169327-87-1
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Cat. No. : HY-100069
M.Wt: 465.09
Formula: C13H4Cl2F6N4O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 169327-87-1 :

Fluazinam impurity 1 is an impurity of Fluazinam with antifungal activity. Fluazinam impurity 1 is active against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani[1]. IC50 & Target: Fungal[1] In Vitro: Quantitative structure-activity relationships (QSAR) analyses of fungicidal activity of Fluazinam impurity 1 against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani are carried out and the results are compared. In the case of S. fuliginea, a usual QSAR equation with Hammett's electronic parameter (sigma-m) and hydrophobicity (pi) is obtained, suggesting that the uncoupling mechanism might be involved in the mode of action. In the cases of P. oryzae and R. solani, QSAR equations are consisted of sigma-m, pi and the activity rank against Botrytis cinerea as independent variables,indicating both of uncoupling and SH-inhibition are working in the action mechanism[1].

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