Talampanel


CAS No. : 161832-65-1

(Synonyms: GYKI-53773;LY-300164)

161832-65-1
Price and Availability of CAS No. : 161832-65-1
Size Price Stock
5mg $96 In-stock
10mg $144 In-stock
50mg $492 In-stock
100mg $792 In-stock
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Cat. No. : HY-15079
M.Wt: 337.37
Formula: C19H19N3O3
Purity: >98 %
Storage: at 20℃ 2 years
Solubility: DMSO : ≥ 100 mg/mL (296.41 mM)
Introduction of 161832-65-1 :

Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity[1]. Talampanel (IVAX) has neuroprotective effects in rodent stroke models[2]. Talampanel attenuates caspase-3 dependent apoptosis in mouse brain[2]. In Vivo: Talampanel (orally administration; 5 mg/kg; once a day; 2 weeks) reduces motoneuronal calcium in a mouse model of ALS, but its efficacy declines as the disease progresses[1].

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