GSK591
CAS No. : 1616391-87-7
(Synonyms: EPZ015866; GSK3203591)
| Size | Price | Stock |
|---|---|---|
| 1mg | $62 | In-stock |
| 5mg | $132 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $370 | In-stock |
| 50mg | $620 | In-stock |
| 100mg | $950 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100235 |
| M.Wt: | 380.48 |
| Formula: | C22H28N4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (262.83 mM; ultrasonic and warming and heat to 60°C) |
GSK591 (EPZ015866) is a potent and selective inhibitor of protein methyltransferase 5 (PRMT5) with an IC50 of 4 nM[1]. IC50 & Target: IC50: 4 nM (PRMT5)[1] In Vitro: GSK591 (5 μM; MCF7, T47D, and MCF10A cells) treatment suppresses breast cancer stem cells (BCSCs) proliferation and self-renewal. GSK591 reduces BCSCs numbers in vitro[2].
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