(1R,2R)-2-PCCA(hydrochloride)


CAS No. : 1609563-71-4

1609563-71-4
Price and Availability of CAS No. : 1609563-71-4
Size Price Stock
5 mg Get quote
10 mg Get quote
20 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-100013A1
M.Wt: 528.56
Formula: C30H39Cl2N3O
Purity: >98 %
Storage: at 20℃ 2 years
Solubility: DMSO : 50 mg/mL (94.60 mM; Need ultrasonic)
Introduction of 1609563-71-4 :

(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC50 of 3 nM in cell-free assay, and 603 nM in cell assay. IC50 & Target: EC50: 3 nM (GPR88 receptor)[1], 603 nM (GPR88 receptor, in GPR88-22F cells)[2] In Vitro: (1R,2R)-2-PCCA (Example 3) is a potent GPR88 receptor agonist, with an EC50 of 3 nM in cell-free assay, and 603 nM in cell assay[1][2]. (1R,2R)-2-PCCA inhibits GPR88-mediated cAMP production through a Gαi-coupled pathway, with an EC50 of 56 nM in HEK293 cells stably expressing the human GPR88 receptor and the GloSensor-22F cAMP construct[2].

Your information is safe with us.