Emtricitabine S-oxide
CAS No. : 152128-77-3
(Synonyms: Emtricitabine sulfoxide; Emtricitabine Degradant-III)
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| Cat. No. : | HY-100096 |
| M.Wt: | 263.25 |
| Formula: | C8H10FN3O4S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Emtricitabine S-oxide (Emtricitabine sulfoxide) is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.
IC50 & Target: Nucleoside reverse transcriptase[1]
HIV[1]
In Vitro: Emtricitabine, an antiretroviral agent is used to evaluate degradation pathways under different stress conditions in order to identify degradation products as prescribed by ICH guidelines. Emtricitabine degrades over 51%, 13% and 53% during acid, base and oxidative degradation respectively followed by formation of three major degradation products (Degradant-I to Degradant-III)[1].
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