Size | Price | Stock |
---|---|---|
25mg | $55 | In-stock |
50mg | $88 | In-stock |
100mg | $140 | In-stock |
200 mg | Get quote | |
500 mg | Get quote | |
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Cat. No. : | HY-101046 |
M.Wt: | 445.42 |
Formula: | C21H23N3O8 |
Purity: | >98 % |
Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Quipazine dimaleate is a 5-HT agonist with a Ki value of 1.4 nM for displaces [3H]GR65630 from 5-HT3R in rat. Quipazine dimaleate shows antiviral activity against SARS-CoV-2 with an EC50 of 31.64 μM. Quipazine dimaleate behaves as a 5-HT3R antagonist in peripheral models. Quipazine dimaleate can be used for neurological disease research[1][2][3][4]. In Vitro:Quipazine dimaleate shows binding efficacy to 5-HT1 and 5-HT2 with Ki values of 230 nM[3]. Quipazine dimaleate displaces [3H]GR65630 from 5-HT3R in rat entorhinal cortex with a Ki value of 1.4 nM[3]. Quipazine dimaleate shows antagonistic properties on the rat vagus nerve with pIC50 value of 6.1, 6.49 and 6.17 for 5-HT2, 5-HT1 and inhibition of 5-HT release[4]. In Vivo:Quipazine dimaleate (2.5, 5 and 7.5 mg/kg, one dose for once; i.p.) affects dietary self-selection of different macronutrient diets in male and female rats[1].
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