Mivebresib
CAS No. : 1445993-26-9
(Synonyms: ABBV-075)
| Size | Price | Stock |
|---|---|---|
| 2mg | $96 | In-stock |
| 5mg | $120 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $540 | In-stock |
| 100mg | $900 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-100015 |
| M.Wt: | 459.47 |
| Formula: | C22H19F2N3O4S |
| Purity: | >98 % |
| Storage: | at 20℃ 2 years |
| Solubility: | DMSO : ≥ 37 mg/mL (80.53 mM) |
Mivebresib is a potent and orally available bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a Ki of 1.5 nM. IC50 & Target: IC50: 1.5 nM (BET)[1] In Vitro: Mivebresib inhibit DHT-stimulated transcription of AR target genes without significant effect on AR protein expression. In addition to blocking the transcription activation downstream of AR, Mivebresib is also a potent inhibitor of MYC and the TMPRSS2-ETS fusion proteins[1].
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